A condition in which the subject exhibits irrational amount of skill and knowledge in relation to the town from which they hail.
Example: Bob- "let's just take Main Street?"
Townie: "nah brah, just take college to Adelaide to division to lee to Kelsey. Wanna get high first? I know a guy. "
Bob: "dude you have a serious case of towns syndrome but yea we can et high."