To take a shit. Stems from the phrase "dropping a deuce" whereas a curveball in baseball is indicated by the number 2.
Mack: I'm going to the bathroom. Gotta throw a curveball.
Jack: Make sure to wipe.
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Intense oral sex from a ghost or any other phantom-like deceased creature.
Fred: I got some good ghoulish gluck gluck at that haunted house last night.
Ted: What??
Fred: Yeah that poltergeist sucked me off real good.
Ted: Bro, are you high?
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A euphemism for masturbating according to people from people who live in towns on the Massachusetts-Rhode Island border.
I was alone at my apartment in New Bedford and feeling horny so I figured I would take a quick trip to Paris.