A skeezer is a gold digger, a ho, a female con artist (figuratively or literally), or in general, a woman with low morals who is out to extract money from others through shady means.
That skeezer tried to jack my watch, my ring, my wallet, and my gun!
Your first,second, or third cousin's child, or, as a literal description of a person's much younger cousin.
How'm I gonna hang out with my baby cousin? We're from completely different generations.