Karen

Used to be an ordinary name.
Now, it's the hot new socially acceptable way to publicly insult women, and have everyone laugh along.
Interchangeable with words like "cunt" and "bitch".
For a while, it was used to describe entitled women who cause trouble in public. Overuse of the term has broadened it's definition to any woman who isn't constantly friendly and agreeable, or a woman who is in any way confrontational.

"That lady told me to move my truck out of the handicap spot. What a Karen."