Acronym based on the phrase "Play The Fucking Objective!" It's used in objective based multiplayer video games like Battlefield when the team is losing because players are doing other things and ignoring the objectives.
A team is losing a game because they don't have anymore flags, and most of the players are too busy trying to get kills instead of capturing flags. A team member will shout in chat or over VOIP "PTFO!" to try and get the team to realize that they need to be capturing flags.
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