A metaphorical substance that when ingested makes an individual, a group, a piece of media, etc ironically funny - especially when their intent was to be serious.
This substance can also be produced by exceedingly funny material, and can be pictured as excreting or discharging from said material.
Jim -in an unironic video essay: you see leafs being green and not red is the very reason we need to have poor people.
Jill -to her friends: Holy shit, that man is dripping with clown juice.