Literally, to trigger an explosion in some sort of secure space, of sufficient strength to breach the doors and allow entry, usually for some nefarious purpose.
By extension: To exceed some form of convention, norm, or expectation by a wide margin, to the point of obliterating those expectations and redefining the conceptual space.
Popularized by Michael Caine's famous line from "The Italian Job" during a bungled burglary attempt: "You were only supposed to blow the bloody doors off!"
They've got no idea how much money 'Fast & Furious 6' is going to make this Holiday season. It's gonna blow the doors off!
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A somewhat more familiar and less pejorative contraction of the word "whore"; often used for comic effect.
Everyone loves Julia Roberts' character in "Pretty Woman"... did y'all forget that she was playin' a ho!?
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