When you are almost to a restroom door/stall and someone cuts in front of you and takes the last spot forcing you to seek out a new place to go.
I was en route to take a huge crap when some turtle hopper jumped in front of me. The turtle was peaking out but I managed to contain him long enough to find another place to go.
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Human pests that infest your apartment/house, eat your food, fail to clean up after themselves, and make life a general pain.
I came home last night and my roomite had not only eaten all of my Captain Crunch, he left the bowl on the counter without washing it.