When an individual is behaving in manner which is deemed questionable by his or her peers.
Boy 1 - 'Have you spoken to jamal lately'
Boy 2 - 'Nah man, that nigga moving irregular'
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The initiation of Sexual intercourse with someone of the opposite sex. but can be used when making reference to some forms of foreplay such as Oral sex.
Boy 1 - 'I saw you leave the club with Lucy, did you activate?'
Boy 2 - 'Nah man she was on her reds'