Surname of the family originally known as MacAonghusa. It is written that they descendeded from Saran, chief of the Dal Araidhe. They would be a part of the Ui Eathach Cobha in what is now County Down and ultimately ruled as the lords/chiefs (both prominently and intermittently) of Iveagh in Rathfairland until the mid to late 17th century. They also held Castle Dundrum from the late fourteenth century until 1601, and for a brief stint from 1642 to the late 1640's.
Some famous McGuinness people include John Martin McGuinness (Irish Republican politician), Deborah Louise McGuinness (co-director and senior research scientist at the Knowledge Systems Laboratory at Stanford University), Ed McGuinness (comic book artist), and John McGuinness (professional motorcycle racer).
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