Means your girlfriend/wife/ex-wife/wish-you-were-getting-some comes first before anything else.
"Dude, you are so pussy whipped for buying your ex-wife diamond earrings on her birthday when she cheated on you with your best friend!"
"I can't go to the basketball game with my best friends cause my wife wants to watch the Sex and the City finale and you stay home!"
"You guy friends are going to the strip club and you go to your woman's bachelorette party for her friend"
When you're laying in bed and your girlfriend or other kicks you in the butt during a joke and it hits your nuts from the behind with 1 nut or 2 hanging by your butt crack
Babe stop kicking me you might hit my back nuts!