Of Mice And Men'd

The act of mercy killing (literally or figuratively) a really close friend of yours because they don't pick up on social cues and can't be taken anywhere because you know they'll fuck something up. Typically used when someone is known for getting too inebriated.

Bro 1: Dude, Lenny was so drunk, i took him out back and Of Mice And Men'd him.
Bro 2: Hahaha so he's passed out back there?
Bro 1: No. I took a gun and shot him in the back of the head. There's blood everywhere.