An expression used similar to "this sucks" or "that was ass." Used in context, big tuph can be used in many ways.
Alternate forms of "big tuph" include:
-big tuff
-big tough
-big tufph
Big tuff (n.): having had something ruff ruff happen to another or yourself
For example...
Kanye: Kim, I hated that concert.
Kim: Yeah, that was big tuph.
Another example:
Joe: Man, I can't believe my dog just got hit by a bus driven by a man under the influence.
Marvin: Damn, that's big tuph.