A copious amount of any substance, usually an illicit drug. The term originates from author Edgar Allen Poe who could snort more coke than any man on earth. His average speed was 5 rocks a minute which translates to 1 kilo per hour making his snorting speed equivalent to a speeding race car.
"Yo bruh check this out I just ought a Poe Load of coke for the party tonight"
"Nice bruh pass me summa dat nose candy bruh"