1. The act of having anal sex
2. A particularly large piece of shit
3. A clenched fist
1. That girl has some freaky badonkadonk, I'd duke her without question!
2. Hey guys I'll be right back, I gotta drop a duke real quick.
3. Put up your duke's!
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To take a shit, usually an especially large one at that.
Every morning I drop a duke, eat cereal, then shower.
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