1. Chemically altered mindstate in which you have drank or done so many drugs you cant feel your face. Or refer to your face as a facey face equals domefaced
2. Out of body experienced induced by high levels of drug presence in one's body.
I was so domefaced last night at that party, i made out with his cat and puked all over after smoking 5 bongs and drinking a handle...of tequila.