Gunkles

Laughing uncontrollably, sometimes for hours on end. Often results in the person pissing their pants, and or soiling themselves. It is considered a disease by certain countries, with no cure in sight.

First case was discovered in a small town known as Marshfield

Byron: Oh no, I think Maria has the gunkles.

Markie: Oh god, somebody get some air sanitizer and some toilet paper!