hoople head

I agree this term came from "Deadwood", but I don't think it means drunk or drunkard specifically. I think a more accurate definition would be clueless bastard or loser or lowlife, or particularly a combination of these.
In the show, these people often tend to be drunk or drinking, but not always.

Go buy the hoople heads a round of drinks.
Go get those hoople heads out of the street, before they get run over.

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