A knock is referring to someone who is a fiend for drugs of any kind. weed, coke, pills, meth etc... itâs like calling someone a druggie, drug-head , tweaker, fiend, or addict.
âHe pawned his familyâs jewelry and tv to get drugs that guy is a straight up knockâ
Drug dealer may say: âIâm going to go serve one of my knocks a gram and Iâll be back in 30â