To take a hit of marijiuana and then chase it with a swig of hard liquor (specifically Tequila, Burbon, Whiskey or some other such drink). As exemplified by Bill Murray and Chevy Chase in the film Caddyshack.
Chevy: (takes a toke of marijiuana)
Bill: c'mon pal fireball it!
Chevy: (drinks whiskey, coughs uncontrollably)
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