Used in reference to something that is at once infuriating and amazing.
Did you know that the slogan for the Fox News Network is "Fair and Balanced" ?!?!
Yep. I did. Isn't it infuramazing?
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Most commonly used as a response to a story involving a female acquaintance that reveals too much information.
You know that she and Rob hooked up in the tent we're sitting in?
What? They did?! That's kerriefying!
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A girlfriend who is clingy, annoying, utterly unattractive (both in looks and personality) and generally dead weight.
Dude, your girlfriend is a Cierr-ugh, you've got to cut the ties.
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