A League of legend term pitched by 'Double Hashtag'. It is a term related to champion performance by your team opposed to the other team. In it's simplicity, it's meaning is that if a champion is played on your team, they will perform badly.
However, if that same champion is played on the opposite team, your opponent will perform superbly . A syndrome commonly found in Quinn, Lee sin , Teemo, Vayne and Draven players.
Oh man, even though last game my draven fed, I bet the enemy Team draven in this game is ganna get a penta kill, fuckin Quinn Syndrome.