To sleep with someone once and that's it. Usually done to someone you're just not that into or has 2+ brat kids you can't afford or don't want to take care of. A one night stand, same as "hit it and quit it" and "fuck and chuck." Named after the NBA rule.
George Clooney and John Mayer are famous one and doner's.
Ted:"Man I wish I could go out tonight and pick up some strange but the wife is up waiting with the kids."
Bill:"Screw all the drama, taking care of kids, expense and sexual monotony a relationship is..I'm a one and done kind of guy!"
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