One of the strongest insults known to mankind. Someone doesn't just have to go fuck themselves but the writer also wishes them to get Rick-rolled, the second-worst thing someone can encounter on the internet (directly after TikTok).
Caroline reacts to friends having a problem with "I've got it worse" so her friends tell her to go Rick herself.
Someone wishes you to get your sleeves wet when washing your hands so you can only respond to them with "to go Rick yourself".