A Sisue is exactly the same as a normal issue you may have but changes to this term when talking to a real sis
Commonly used when discussing relationship problems
Sis im having a real sisue at the moment, can you help me out?
Apparently a Scottish surname usually given to short white midgets who date people taller than them.
DISCLAIMER- It sounds suspiciously French but i assure you its Scottish
Look its ****** Lamont doesn't she have a boyfriend
Yeah hes got abs!