cancer

A vicious person who is extremely negative and adversely affects the mood and demoralizes those around him/her. He/she cannot be fixed or changed and needs to be cut out of the system, or the pathetic nature of the person will spread like wildfire and create an everlasting hostile environment.

The director of international relations is cancer and needs to be canned. He whines like a baby, sabotages other's projects, and is flat-out an ingrate.

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