Scoots

Another term for having diarrhea.

"My buddy just texted me and said he's got the scoots so he can't go with us"

10-Ply

A 'soft' person, particularly a man who lacks toughness; 5 times as soft as 2-ply toilet paper

Man, he can't fight he's definitely 10-ply.

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Cannon

A very large marijuana joint.

"Man you've been smoking one-gram cannons. How are you still conscious?"

Calvins

Boxer-brief style underwear; short for clothing designer Calvin Klein

Girl: Do you wear boxers or briefs?
Guy: Naw girl I wear Calvins.

The Rez

Short for Native American Reserve or Reservation; territory where Native Americans reside and do business.

Friend 1: Did your sister leave for college yet?
Friend 2: No she has to finish packing so she can leave the rez later this week.

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Poopy Pants

A downer, sulker, belly-acher, killjoy; being cranky or grumpy

Guy 1: Man what's wrong with him?
Guy 2: Oh he's just being a poopy pants.

Soft No

Another way of saying "Probably not"

Guy 1: Hey, can we stop at the liquor store real quick.
Guy 2: That's a soft no.