Interchangable with "nuts", in every way except when referring to a literal nut.
1. "I think you're nutes"
2. "My friends think I'm completely nutes"
3. "the way he turns on the television as soon as he walks in drives me nutes"
4. "the fans were going nutes"
'Nutes' is interchangable with 'Nuts' in every way, excluding using the word nuts as in the food.
Comes from a gif of Mario's dad from The Super Mario Bros. Movie saying "I think you're nutes.".
Hey check this out!
WTF! that's fucking nutes!