A girl that has an extreme interest in something; most often used for girls that love a particular celebrity. There are multiple kinds of fangirls, such as music fangirls, actor/actress fangirls, and anime/manga fangirls. There are also sections within those, but I will not go too in depth.
Some fangirls may get offended when associated with other fangirls. For example, if an anime/manga fangirl sees a post on something, such as tumblr, that is titled as "Fangirl Questions" and promptly reads it, only to find that it is aimed towards music fangirls, she may get very angry and begin to type something extremely angry at the person whom posted it.
"She is a fangirl."