I On Run It.

A utterance that came from Melo telling a girl that he doesn't run his own Instagram account, so he couldn't necessarily follow her back.

Another definition, referenced her as an "ugly b*tch". When she comes of age she will be a 8.3. She is athletic, curvy, cute, carmel skin toned young woman.

Kim Kardashian replied, "I on run it." When asked about a specific Instagram posting.