While commonly associated with a promiscuous woman, in all actuality, a "ho bag" is an overnight bag with a change of underwear and personal hygiene items for freshening up after a one night stand.
"Dude!! I'm about to take that skank home and knock the bottom out of that! Good thing I got my ho bag in the trunk."
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The area or region immediately surrounding the scrotum or groin area, including the scrotum itself.
"Dude!! I need to hit the showers and wash my scrotiferous region...BAD"