Struggly

A state of being where one is struggling to function physically and/or mentally, often after a hangover or serious illness.

Mike: Are you coming out tonight?

Not Mike: Nah, I'm still feeling struggly from the flu. I'm gonna take it easy today.

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Gina: You look like death, what the hell is the matter with you?

Not Gina: Mmmph, too much to drink last night. So struggly. Go away.