When something has an effect on something else, and it is AWESOME.
That impromptu rave last night had a real pimpact on my Great-Aunt Marjorie.
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Used in British English to refer to someone who is insane.
Also probably the most common mistake made by outsiders when trying to reproduce a British accent. For the record, it's either "he's a nutter" or "he's nuts". Saying "he's nutters" is a good way to make British people dislike you.
Good: "What are you, some kind of nutter?"
Bad: "Are you completely nutters?"
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