Basically "seems" but misspelled. It can mean anything depending on the context.
Alex and Josh are Friends, but Alex was arguing with Tim:
Tim: Hey, wanna meet somewhere?
Alex : smees
Tim: ok loser
Josh: wanna hang out later?
Alex: smees
Josh: great, cya later
Amy's grandpa died:
Amy: My grandfather just died
Hannah: smees
Amy: thanks, you're a good friend
A heated argument between Billy and Eric:
Eric: Your mom is gay and you stink, you dumb asshole
Billy: smees
The Crowd: Oohhh, burned!