Officially, it is an acronym meaning Cystic Fibrosis Conjuctance Regulator, but to those in the know, it actually means Clit Fingering Tit-Rapist.
Teacher: Okay we're learning about genes and differentiation today. Anybody know what CFTR stands for?
Georgie: Is it clit fingering tit-rapist?
Teacher: ...no.
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Wanking yourself off. A reference to "strumming the guitar" which means sex.
Person one: Hey, wanna play COD4 later?
Person two: No mate, I havent strummed the guitar in ages so I put aside some time later for a guitar solo.
Person one: Dude, ew.
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