undrunkable

the inability to feel drunk during a day/night while drinking heavily. Usually occurs the night following a hangover.

Many have tried to fight this condition by keeping on drinking despite the lack of effect, this usually results in getting sick before feeling drunk.
The irreversibility of this condition has been disputed as some claim to have succeeded in eventually getting drunk.

tom: dude, last night was really lame
mike: really? i heard everybody say it was a sick party!
tom: well, maybe it was, but i was undrunkable..probably from drinking so much the night before...anyway, i gave up after a couple hours and just went home

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