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A sarcastic expression said around a girl who is unattractive just to be a douche. Generally said in a unusually high voice. Also, You generally add the girls name after the Oh Yes part.
Schuyler-OH YES KELLY!!!!
Kelly-SHUT UP OR I'LL KICK YOU!!!!
Winnie the Pooh's way of saying Motherfucking Shit.
Piglet: Pooh, you're out of honey!
Pooh: oh bother.
A reaction to a pick-up line, comeback, burn, or diss that was, at first thought, great, but upon further examination revealed itself to be a) stupid, b) creepy, or c) just plain tragic. Usually starts with great enthusiasm only to die down very quickly.
Guy 1: Boy your mama's so fat they had to use an atomic bomb to make a crater large enough to bury her in!
Guy 2: HEY-oh.
When Winnie the Pooh means "Goddammit"
Piglet: Oh no! Tigger's bounced all over the vegetable garden and ruined the carrots!
Winnie the Pooh: Oh bother!
This odd phrase is similar to "oh my land," with the interesting addition of hailing the stomach-acid-reducing medicine.
Oh mylanta, it was bad!
n. An erection.
int. An exclaimation used to note an erection.
"I saw Natalie today--"
"Uh-Oh!"
"..."
"You gave me an Uh-Oh"
"Well it wouldn't be the first time."