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Random
Person A: Don't make me derp
Person B: What do you mean
Person A: Just start violently coughing at you. Derping
"I was mid-cough when the character scared me; really had me derping."
"Don't watch scary movies while sick or you might end up derping."
When you're scared and coughing at the same time
Callmekevin was derping so much in his last video!
Being scared and coughing simultaneously.
Oh god, I was playing this game and I started derping so hard!
Bob: Hey! What's wrong with Kevin?
Pierre: Don't worry, he's just derping because he keeps dying in the scary game.