Used in a positive way to say that something has really made your day.
Doctor: "Yo, bro, you don't have cancer anymore!"
Bro: "Whoa! That really swizzles my diggle!!!"
Antiseptic mouth rinse required prior to performing oral sex on a particularly small or fragile penis.
Other doctor: Did you see the tranny in the ED tonight? Super hot!
Doogie: I know right! I had to turn down his or her blowjob offer... couldn't find the magic swizzle.
When someone, usually a repair person or utility worker, is causing seemingly intentional delay of a plan or schedule. Similar to being "jerked around" or "led on". More common usages: swizzle fisted, swizzle fisting
The swizzle fisting repair guy hasn't shown up yet but it was supposed to be done yesterday!