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A disease caused by the act of using your own shit as lotion to jerk off.
Damn I think he has Johns Disease
Having one foot larger than the other.
Sam: Yo, dude I have Horton's disease.
Bill: What? Is it catching?
Sam: Well check your shoe size and find out?
Where the anus becomes enlarged and inflamed, so enlarged and inflamed that it eventually encompasses the whole personality and being, in other words the individual turns into a complete asshole.
when you think about it, every person knows someone that has bagnasarian disease in their bloody life, unfortunately it can be contagious.
When one is Experiencing a repeat cycle of dealing with and or dating a fuck boy or fuck girl
My corn disease is flaring up.
Somthing as fugly as a wart yet that much more to be diseased
Shannon is the sluttyest diseased wart known to man kind
a fatal condition consisting of other smaller diseases, prime examples being "shot in a vital organ disease", or "crushed by a flaming helicopter disease".
The symptoms can range from completely underlying to incredibly painful, and the life expectancy for a dying disease patient can range anywhere from 0.5 seconds to 20 years.
"I just came back from the doctor's, and he diagnosed me with dying disease."
"Maybe it's because you've got rebar through your forehead"
Abnormally Large Penis disease.. no, it's not actually a thing but if you're a twelve year old boy then you probably think it is..
The doctors diagnosed me with APL disease, and I couldn't agree more.