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Pick-up-till-put-down Syndrome

A disease caught by picking up too many cards in UNO when playing by the rule "Pick up until you can put down" when needing a card.

Michael:"I Change colour to Blue"
Nick: "Darn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
John: "Oh damn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Ash: Bro he's got Pick-up-till-put-down Syndrome!
Nick: (picks up card)
Nick: Finall-wait nevermind.

by NinjaSlayer_936 January 2, 2021


down river syndrome

When a person has chromosomal damage from living down river near Detroit

Man that guy has a bad case of down river syndrome

by Kauai-kimo September 23, 2022


dj down syndrome

Samsquatch, jef

My name is DJ down syndrome but you can call me Jef

by DJ DOWNSYNDROME November 20, 2017


Yes in a down syndrome voice

When someone says yes but like they are missing chromosomes

"YEEEEEESSSSSSS"
"oh no hes doing yes in a down syndrome voice"

by WildWillez December 13, 2020


Dicked Down Syndrome

Temperamental shift in females caused by increased testosterone levels stemming from big dick driven polyamory and excessive sexual intercourse. Leads to a reduced ability to pair-bond and leads to a shift in sexual selection choices (from "preference seeking" to agreeableness and stability). Tell me that I'm fucking wrong though shit-brains.

Iam "Did we do one on Dicked Down Syndrome already?"

Hym "Hmm? No... I don't think so..."

Iam "Then how did predictive text know that 'ability to' would be followed by 'pair-bond'?"

Hym "Hahaha! Even the predictive text knows it's true!"

Iam "We must have used that line before..."

Hym "I'm surprised we haven't used 'big dick driven polyamory' until now. Seems like we've been sitting on that on for a while. Just like the $10 and hour whore! Bah dum tss! HAHAHAHAHAAAA!!"

Iam "I'm serious though. If only 3% of the population have 'dark triad traits' and we don't know why women are attracted to them; how for you account for the other 7-17% of men who are hyper-attractive to women?"

Hym "You account for it with big fat cocks. They're attracted to 'dtt' because sometimes people with 'dtt' have fat meaty dongers and your daughter loves it. Hahahaha!!!"

Iam "I mean isn't it strange that he never asks what the commonality is between the hyper-successful men with 'dtt' and those without?"

Hym "Remember how she started crying when we called her a $10 whore to her face? HAAAHAHAHAHAHAHAHAAAA!!!"

by Hym Iam April 13, 2022


Down syndrome pedro

A Snitch who tells a guy/Usually his brother about jerking off in a forest

You Bro You hear that guy is a down syndrome pedro No way bro

by Canadian beastiality June 28, 2020


Down syndromic

Just another way to call someone with Down syndrome

Look at that retard he’s so down syndromic

by Sellout President September 5, 2023