1) Having messed up so bad that one has done the exact opposite thing one was trying to do
2) Having accidentally lost progress instead of gained
3) Trying to use the down escalator to go up
“The calming medicine has only made the ape more angry!” hollered the scientist. “We’ve gone up the down stairs!”
The men walked out of the maze entrance, frustrated that all the paths they took had only led them up the down stairs, as it were.
Alice wasn’t very bright at times, seeing as there was many an occasion where she was going up the down stairs at the mall.
A disease caught by picking up too many cards in UNO when playing by the rule "Pick up until you can put down" when needing a card.
Michael:"I Change colour to Blue"
Nick: "Darn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
John: "Oh damn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Ash: Bro he's got Pick-up-till-put-down Syndrome!
Nick: (picks up card)
Nick: Finall-wait nevermind.
When receiving a head job, the giver strokes the penis in an up and down motion whilst turning their hand 180 degrees at the same time
How’d ya go last night mate? Bro, best up down 180 I’ve ever had
The art of makimg a girl go up and down by having sex
Im making my gf to moan very loudly by getting her going up and down while on top of me
It means you’re forever with your partner.
Rhys: “Shawn was doing the Four fingers up and middle finger down in his post” .
John: “bro he must love her then for real”.
a game from chowder that involves no winning
its bad luck not to say the whole name
how many times do i have to say there is no winning in Field Tournament Style Up and Down on the Ground Manja Flanja Blanja Banja Ishka Bibble Babble Flabble Doma Roma Floma Boma Jingle-Jangle Every-Angle Brickabracka Flacka-stacka Two-ton Rerun Free-for-all Big Ball.
What the cantankerous Homer Bedloe gets stuck with doing every time he misses the Hooterville Cannonball and is therefore forced to take a manually-pumped hand-car along the tracks that run from Hooterville to Pixley.
The ultimate "puffed-up dandy-dude getting cut down to size for once" recurring gag-scene from "Petticoat Junction" is when Mr. Bedloe --- while embarked on yet another failed mission to scrap the Hooterville Cannonball --- is forced to perform his classic "Up, down! Up, down! Up, down!" routine with the handcar-lever as he solo-races a clunky hand-car from Hooterville to Pixley after he's either missed the train or is otherwise somehow prevented from "riding in style".