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To literally go insane, usually accompanied by flailing arms, incomprehensible gurgling noises and a crazed look.
Did you see that guy going down the residential area at 110 mph? He went through someones fucking lawn, THEIR GODDAMN LAWN AND THROUGH THE FENCE TOO. God, then he got to the orphanage, it was a massacre. I tell ya man, he was going ape shit.
To become very angry.
The boss went ape shit when he heard the bad news.
Someone who goes completely "Ape Shit" over something means that someone goes completely crazy over this object, person, place or thing.
"Dude, did you SEE that?" said Brooke.
"No, what was it that you saw?" replied Brian.
"The Famous Butter just went completely APE SHIT on the mic!" said Brooke.
And let your dyko, bass playing girlfriend had to have in the backseat with a yoo-hoo bottle or she went apeshit "Frank Zappa"
To become overly enraged, to a level bordering on psychosis
Savy Dog would go Ape Shit every time Chimpy sang Queen of Hearts by Dave Edmunds, as he was lining up his tee shot
fecal matter derieved from the anal cavity of an ape
"Woah! Look at that! He stepped in Ape Shit!"
Verity going ape shit on herself with a wine bottle.
Ape shit, steam forming masturbation