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Typically when you finger a girl up to your knuckle. Sometimes when two men try and finger each other.
EX. I got fucker knuckled last night and it felt great!
EX. David and I need to try to fucker knuckle tonight.
As pertains to construction site or job site lingo
A worker or person who is constantly screwing around and challenging rules, playing pranks, smoking cigarettes inside the building, being a general pain in the ass.
Listen here Fucker Knuckle! Rules are rules! If I catch you smoking in my building again, I’m gonna call your boss and have you removed from the jobsite.