A state of mind sometimes found in academics and intellectuals who become so wrapped up in their intelligence and their studies (their "Ivory Tower") that they become disconnected from the rest of the world. Often produces attributes that make for unpleasant social interactions, ranging from severe shyness and introversion to arrogance, haughtiness, and pride.
Dr. So-And-So used to be such a great person until they started working in academia. Then they started losing touch with the world around them and developed a severe case of Ivory Tower Syndrome, and now they think everyone with an IQ less than 120 is an "ignoramus."