This axiom, regardless of its origins, has been common in post-victorian Britain as an abbreviation of 'to mind your manners' or, more specifically, to say both 'please' (p's) and 'thankyou' (thank-Q).
Thus the phrase 'watch your p's and q's' has been in use to encourage people to speak politely, especially children, who remember such phrases better than just instructions.
Kid 1: You spill my pint?
Kid 2: feck off!
Mum: Oi, watch you're p's and q's!
Kid 2: Sorry. Feck off, please.
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p's = paper as in money
q's = measurement of drugs
"on my p's and q's"
song by kano
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Shaortening for "Pints and Quarts", which were the two main measurements for drinks. Whereas now we use pints, half pints, shots etc, there used to be Pints and Quarts.
Whehn things got rowdy, as they tend to do in pubs, you'd normally hear something like "Mind your Pints and Quarts" and a warning or some such. this was shortened to "mind your P's and Q's"
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(Term of phrase used by some and understood by few...)
P's = Priorities
Q's = Qualities
"Mind your P's and Q's."
In lamens terms: Always remember that you have "priorities" in life, and the "qualities" of your character will help you achieve them...
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A packet of M n' Ms in GTA V. Probably means something else comedy-wise that I don't know.
GTA Online player 1: Let's go buy some P's and Q's!
GTA Online player 2: Okay!
*Blows up car*
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Smile/Face of person holding hands over ears
Symbolizing he/she is not listening
person A: Blah Blah Blah Blah
person B: q>_<p LALALALALA NOT LISTENING
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