Too far gone

When a female is messing with the wrong dude and you are trying to get it but she is (too far gone)

Harry-Hey bro you getting it with saara yet?
Colin- Nah man she’s too far gone.

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he has gone far

He has gone far means he has psychiatric desorders after an event/choc and has bot be cured in time. After a while, the Disorder is deeply rooted and the patient is hard to reach by a Therapist.

After the death of his wife, he has been isolating himself from his friends for many years. Now, he has gone far