Two knuckles deep refers to somebody who is digging for nose boogers while face to face with someone or a group of people, not hiding the event, letting everybody see the activity.
Victoria: Did you see that?!? Chad just went two knuckles deep!
Steve: Two knuckles deep?
Victoria: Yeah! He was digging for nose boogers right in front of us!
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To finger fuck a girl, using several fingers at the same time. Usually implying the girl is very arroused.
"That chick is so damn hot! I'd love to be 3 knuckles deep stirring the soup!"
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Puting you arm past the elbow inside somebody
Im gonna fist you so hard I'm going sixth knuckle deep!