Sticking your big toe into a vagina.
Susan was thrilled when Bigfoot showed up to the party because she knew it would be the best nitty gritty she's ever received.
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Pitties (or tits that hang into a girl's armpits when she's lying down) that have gotten all sandy or dirty.
After a long day at the beach, her pitties became nitty-gritties.
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“Nitty-Gritty” originated in midst of the 18th century slave trade. Ships often carried slaves in the cargo holds below deck and nitty-gritty now means getting to the bottom of it. This is a derogatory reference to the slaves which were held at the bottom of the vessel.
“Getting down to the nitty-gritty”
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The art of Being fisted by someone wearing a sandpaper glove that has been dipped in glue and rusty nails.
I'm sorry I can't go horseback riding today, I received a nitty gritty rusty fucker last night.
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1: Da minuscule-but-abrasively-hurtful details dat Elliot Ness had to deal with in regards to Al Capone's right-hand-man henchman.
2. Da unpalatable and irritatingly-picky details regarding actual history of whether said smug sleazeball actually performed many of da entertainingly-memorable felonious actions portrayed in da 1987 "The Untouchables" film.
Da wildly-popular "war on liquor" gangster-drama starring Kevin Costner and Robert De Niro may indeed have been exciting and dramatic for its viewers, but if you get right down to da Nitti-gritty of it, da infamous "goon in a white suit" character played by Billy Drago apparently never personally performed hitman-style assassinations as depicted in said movie, nor was he actively involved in much if any actual killing, either.