Off-one

To get sober. Or more commonly referred to quitting methamphetamines.

Hey, I'm sorry but I can't chill with you guys at the tweaker pad anymore...I'm trying to stay off-one for good.

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Off one's rocker

To get angry, frustrated, or irritated to the point that you suffer a tantrum of sorts

Anna: How was tennis, Tim?
Tim: Rubbish. I lost to Aidan. I should try and keep a level head and not go off my rocker when I play...
Anna: Yes. One should never go off one's rocker. Now it's time to eat some squirrel pie.
Tim: :l

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off one's trump

Unhinged; temperamentally unsuited for one's position.

The White House staff is off one's trump; they cannot give a consistent explanation for the incriminating Russian collusion stories.

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Blow off the easy one

Another term for masturbating.
To blow off refers to the act of masturbation, and the easy one refers to the penis

Me: "What are you doing tonight?"
Friend: "I'm gonna blow off the easy one"

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bite off more than one can chew

Try to do more then you can handle.

You might bite off more than one can chew if you I take a second job at night.

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Off One's Base

adj. A person that is crazy or behaving in idiotic ways

"you are so off one's base"